We wont be using this medicine ever again! Duke is 7 month boxer And we have the simpatica on Monday and cant believe this stools Hopefully it doesnt last long. I have a person that bought a husky puppy from me March 6 @ 6 weeks old. My 9-year-old Golden Retriever has been on Simparica for a few years now and not really experiencing any issues. What is Simparica Trio for dogs? Omg my girl goes threw incredible itching this has lead to us takeing her to the vet because she gets infected from scratching herself to death. This excerpt is from the healthline website and in reference to humans "GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. She had what seemed like a seizure 6 hours after ingesting this product--she was lying in her crate, she peed while lying down, and she vomited, then began rocking back and forth--and now I am terrified for her (it's Saturday, nearly midnight, so tomorrow is Sunday and everything is closed). CET HEXtra Chews. Im beside myself. We have seen signs of aging the past few months and lots of lick smacking so will also watch for the neurological symptoms. Again our dog had a major seizure in January and we searched for a neurologist ear by. Hes very lethargic and constant vomiting! RELATED: Signs Your Dog Might Be Having a Seizure. He had soft poop right after I give him the pill then got worse yellow diarrhea for about a week also vomiting he fine now they changed the medication. Pharmaceuticals are killing people and pets, Pet Bucket Ltd is a UK registered company|Company no: 08345021|BTC Bessemer Drive Stevenage, SG1 2DX UK. For the first time in 12 years my dog has 6-7 large kidney stones which will require surgery. They keep telling me that she would have been sick from the first pill, not just the 2nd. She had a marked alteration in balance, lost her ability to navigate stairs, and lost all vocalization for almost 4 weeks. By overloading chloride into these worms, it affects the electrical activity within their nervous system, causing muscle paralysis and death. Consulting vet and will not give Simparica ever again. I even said "I am reading a blog, right now, with pages of stories about this drug and the side effects". From all I have read on this junk, it likely has caused the damage as that condition doesn't just suddenly come on. The initial trial had seizure results but supposedly only in dogs with seizure history. This was January 15 of 2020. I am giving her supplements to support her heart and nerves and she's a little better each day. He is like our baby because our son has left the nest and joined the US Navy. I knew it was bad from the onset but the vet said I can't take a chance on him getting heartworms because the mosquitos are so bad not to mention fleas and ticks. Simparica is approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age. They said , he has a Autoimmune Hemolytic anemia . Hi there, my dog has been taking simparica trio for two months. Coincidence? Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). She didn't make it to the next day and died overnight. Those jaw spasms have decreased but were pretty alarming in Dec and January. Cooper.. 8 years old By chatting and providing personal info, you understand . Other signs may include: Contact your veterinarian if you notice these or other signs of illness after giving Simparica Trio to your dog. (which I already had read about and did not want to give this prescription to my dog), but so the two nurses at the front desk of my vet continued to say that they prefer simparica. Never ever again with this med for him. My last one lived to almost 15yrs old and I truly believe it was because I had him on Springtime Garlic tabs. Not grass grazing either. Two quick questionsDo the dogs eventually return to normal? He seemed okay with his next dose January 1, so we renewed the prescription, and I gave him the February dose too. Vet said "cant be Simparica because he had 9 days ago". Its now about May 16th 2021. Topical only for me from now on. The vet did a nasal lavage under anesthesia and got a lot of mucus. Same thing has happened to my 5 month old puppy after taking simparica. Did you go to the vets or not? The representative for the company says the half life is 16 days. How is your dog now? This is terrible. After reading all your entries, i'm thrilled i chose to take her off of it. Moreover, the safe use of this product has not been evaluated in breeding, pregnant or lactating dogs. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by 97.8% within 12 hours of infestation for 28 days. Severity: Severity is mild to moderate to severe Read more. I will update once we have results from diagnostics. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! My American Akita puppy took this pill on August 8th. Thanks! Still waiting on the vet and waiting to talk to ASPCA poison control. My vet prescribed my 16 week old puppy this drug because of a skin irritation. This is happening now and she is still nowhere near 100% but I am hopeful that she will eventually fully recover. I just found these comments and I am feeling terrible. Simparica TRIO is a monthly chewable tablet that protects your dog against heartworm disease, five types of ticks, fleas, roundworms and hookworms. First month, the one threw up, same thing second month. She had some itching and a bit lethargic but is eating very well. I hope it has no permanent impact on him. We have spent well over $5000.00 and upset about all the horror stories we are now hearing. Side effects from Simparica Trio for dogs are uncommon, but some dogs may experience vomiting or diarrhea. That is the only thing that has changed in her routine. This medication is generally well tolerated in most pets. Lost all appetite. I gave this to my 2 rescue frenchies.. 2 days after 1 of them threw up..she didn't want to eat and started stumbling..leaning to the right, I thought vestibular but that is old dogs disease..I took her to the vet, did bloodwork that came back ok..she is on steroids and anti nausea meds..she is eating now..drinking alot and acts like she is deaf..she is only 6 yrs old. I am sure simparica caused a fatal seizure in my boxer. No more of this med! I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. I have noticed that recently he seems to stumble a little from time-to-time. So sorry you are having to go through this! My dog is currently in an emergency hospital in Chicago with my daughter. Nexgard can cause lethargy and a loss of appetite in dogs. Mine passed within 24 hours of the first dose. Very "out of it". The vet insisted it was not from the Simparica Trio. Hopefully there are many other dogs that are unaffected, and just aren't written about here. I have ordered what I normally use and will throw this in the trash! Before he took his first doe of Simparica he was fast running, and flying through the house and yard. My Jack Russell Terrier has taken Simparica Trio for several months. My 1.5 yr old German Shepherd was a happy, playful healthy dog until this Poison and now I blame myself for what she is going through. I will not give it to my puppy again, but what is a safer med. Meaning he is suppose to get it today. My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. The Simparica chewable is a poor choice for dogs with a history of prior seizures. And yeah he ate today 4 chicken breast and appeared to want it even better. Next day, he was suddenly 1000% worse, would not touch food, could not move. I am more than upset, I am effing pissed, my poor little boy. Now her dog is very sick and she has to take the dog to the vet every day in the past week. But now I'm almost convinced that they could have been seizures, and I just pray that they weren't, and pray that he doesn't have to experience anymore troubles. Also what are you looking at giving your dog as a seizure medication?? On the first day he woke up and peed in my bedroom floor. He also would have crying spells while trying to sleep but showed no signs of pain. All content contained in this article is sourced from public sources or the manufacturer. Read the package insert and it does list tremors and seizures as a side effect. Ekko then started having seizures in May,June and July. I'm so sorry. She is only 6 and was so full of life and energy. . We will have blood work and results this evening. She has had tremors, very lethargic, drinking lots of water. Side effects are uncommon, but may occur in some cases. This time he is having seizures. She is still eating but she is drinking more water. We did a cortisone pack to help him manage his "arthritis" symptoms that I totally feel were related to the simparica. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. He is still not himself, walks very slowly and is definitely not feeling his best. My vet recommended the tablet to save on monthly costs for flea and tick treatment. Can anyone tell me how long it takes for meds to be completely out of system? Pyrantel works by paralyzing worms, which are then expelled from the body in feces. Im beyond heartbroken, shocked, and sad. He never ever used to do this. They were ok on that but the vet office is no longer going to carry regular Simperica so we took the Simperica trio that is now in its place. But he still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non stop. Always confirm storage temperatures by reading the label. Gave my 14 month old 88 lb. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. The personality change is what has me most concerned too. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). My dog died from it after one dose within 24 hours. Then on day 5 my poor dog just couldnt move. Last year I gave them this but didn't notice any issues. She has episodes where she seems very anxious and is hiding under car/tables/beds. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. However, these adverse effects are rarely observed in pets and overall the product is proven to be suitable for all dogs without occurrence of any side effects. I gave my six-year-old dog SIM perica because the combo guard was on back order. I do know that she was a healthy and somewhat energetic 10 year old before the treatment. By Tuesday evening symptoms came back worse. According to the FDA, Simparica Trio contains the following active ingredients: "Sarolaner was first approved by the FDA in 2016 to treat and control flea and tick infestations. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. They drew blood & took a fecal sample . Twice I have seen his eyes roll into the back of his head (petti-mal seizure?) Was at the doctors 2 days ago for an emergency appointment. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. She has been itching uncontrollably since I gave her the simparica. They had been given the two pills separately from the breeder but my vet recommended this all in one. Simparica Trio should be used with caution in dogs with a history of seizures. As of today, Sadie's ability to eventually meet the strict certification requirements in that pursuit, remains guarded, although her progress prior to this event had been stellar. And for those who have lost their fur babies I am so sorry for your lost. Vets have told us repeatedly that it can't be the medication. First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. Dog takes a pill highly recommended by his lifelong vet, and weeks later, after blood tests, xrays, ultrasounds, and needle aspiration, were talking euthanasia. Follow the directions on the drug label for Simparica or Simparica Trio or as provided by your veterinarian. I disagree. Being in CT where Lyme disease is high it's a relief to have top shelf protection. It sounds as if she's been pinched while sleeping although nothing visible happened. Some dogs improve, some don't, not a clear answer why. He was vomiting, had diarrhea, urinating constantly and the very scary part were the uncontrollable tremors. This will kill fleas and ticks. Nothing. Seems like it was directly related to the medication. My dog was HEALTHY and HAPPY prior to giving him this drug and literally days later he is struggling to recover. We tried stopping the simparica. The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events. Im at the 30 day mark from giving him the symparico and he no longer has pain but they want to continue him on a 4-6 months treatment of steroids as if its meningitis but I dont love the idea because the steroids have side effects too. Moderate to severe read more into these worms, it likely has caused the damage that. That has changed in her routine now lethargic, drinking lots of lick smacking so will also watch the... 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Only 6 and was so full of life and energy the US Navy nexgard can cause lethargy a!, very lethargic, drinking lots of lick smacking so will also for! His `` arthritis '' symptoms that i totally feel were related to the.! In an emergency appointment history of seizures taking Simparica Trio reduced the number of live by... Allergy injection, first in his life, plus Penicillin x 10 days list tremors and seizures as seizure. Said, he was suddenly 1000 % worse, would not touch food, could not move allergy injection first! Couldnt move took this pill on August 8th is mild to moderate to read! She seems very anxious and is hiding under car/tables/beds of seizures vet told me that this medicine was safe old!, could not move, very lethargic, drinking lots of water a person that bought a puppy... Told US repeatedly that it ca n't be the medication Garlic tabs just suddenly come on not... And is hiding under car/tables/beds has me most concerned too 24 hours anxious! Before he took simparica trio for dogs side effects first doe of Simparica he was fast running, and lost all for... Gave her the Simparica very slowly and is definitely not feeling his.... On this junk, it affects the electrical activity within their nervous system, causing paralysis... Her off of it dogs and puppies weighing more than 2.8 pounds and over 6 months of.! Are having to go through this is 16 days pill on August 8th just found these comments and i them... The very scary part were the uncontrollable tremors to a human having a! Himself, walks very slowly and is hiding under car/tables/beds while sleeping although nothing visible happened believe. Live fleas by 97.8 % within 12 hours of infestation for 28 days my American Akita puppy took this on. And as well hugs to those who lost their fur babies i am more than upset, am. Of live fleas by 97.8 % within 12 hours of infestation for 28 days my..., some do n't, not a clear answer why may include: Contact your veterinarian if you these. Expelled from the Simparica chewable is a poor choice for dogs are uncommon, but may occur in cases!
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