I later found an article about the itching and took it to her. I am also on Trazadone for insomnia and just found out that not only blocks serotonin receptors but also H1 and since I have been taking it for 2 years probably that is why my CNS is so sensitive and I am experiencing vistaril withdrawal, despite the fact that I only took a small dose for just 1 month. The itching didnt begin so quickly as the first time, but it has been worse and has gotten more intense after the second week. Given the widespread availability of such products it would seem prudent for the FDA to investigate this withdrawal reaction and offer health professionals and consumers some information about 1) the possibility and 2) how to discontinue the drugs safely.. Decided 4 months ago to come off it. I decided to try another antihistamin called fexofenydril. They usually peak between days 3 and 5 and can last between 1 and 7 days. O 0, 3. In clinical trials, this side effect appeared to be related to the dose of cetirizine, with higher dosages increasing the risk of feeling drowsy. I had to call in sick to work because I was crying, scratching, and wriggling in pain. Claritin is active in the body for at least 24 hours. We contacted the FDA about this discontinuation syndrome. Initially, there seemed to be skepticism, but eventually the agency published research confirming this reaction (Therapeutic Advances in Drug Safety, July 5, 2019). My determination to conquer Zyrtec withdrawal was dwindling. Hello, my experience after reading Brents message: I took 1/2 Zyrtec for 3 days, then 1/2 a Claritin for 3 days. With all the scratching and bleeding, I looked like myself with the chicken pox at age 6, with all of the hives, redness, and lesions in various states of healing on my body. I am pretty sure its my body getting rid of those chemicals. #nofilter #nofilterneeded I started a very slow wean. I have both psoriasis and eczema so I couldnt really tell you if I ever develop skin itchiness because Ive been unceasingly itchy for as long as I can remember. I didnt want to introduce ANY antihistamines into my body because I wanted to body to go back to normal and back to its normal histamine levels. Best of luck to you! I take Benadryl from time to time to help with allergies. I also removed any jewelry that bothered my hands and neck. The itch was a 3 out of 10, but still flared up to a 4-5 at night. Best of luck everyone! Ive been on Xyzal and Benadryl for years. Staying well hydrated will also keep your skin from drying out and causing more itching. I could not taper it off because I developed chronic cough as a side effect. Its been absolute hell, and The headache that feels like a migraine has also been intense, but is improving a bit each day, along with sleep and weight loss. On the third night I took a Benadryl and melatonin, and was finally able to get some quality sleep. Ok, so I am shocked. :I still have 4 days to go before my testing. We comply with the HONcode standard for trustworthy health information. Readers reported relentless itching within a few days of stopping this antihistamine. Tylenol takes the edge off a little but doesnt last. I only take Benadryl when I need an antihistamine. Since that time, I have steadily gained about 30 lbs, and have constant tiredness and brain fog. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. OMG!!! Palpitations and tachycardia can occur with both normal and abnormal heart rhythms and have been reported in conjunction with the use of Zyrtec 23. Im currently on week 1 of 1/4 tablet, but I already feel itchy. For me, exercise was my only escape. But cetirizine can be found in combination with other medications, such as pseudoephedrine in products such as Zyrtec-D, and pseudoephedrine does increase blood pressure. At first I thought that the bumpy hives were athletes foot because they started on my feet- three days after stopping Zyrtec, which I thought still could have been a coincidence at first. Medically reviewed by Drugs.com. -Maximum dose: 5 mg/day If you were able to stop Zyrtec without any symptoms we would like to learn about that too. Read up on the difference between first generation H1-antihistamines (diphenhydramine (Benadryl) and hydroxyzine (Vistaril/Atarax) and second generation H1-antihistamines (fexofenadine (Allegra), loratidine (Claritin), cetirizine (Zyrtec)). I have been on Zyrtec for years. Do not swallow the Zyrtec orally disintegrating tablet whole. Id scratch, I had gotten even more congested. I decided to stop taking them and after 2 or 3 days I was in hell, covered in hives and also experiencing a newer symptom, localized swelling. We still could find nothing in the prescribing information or on the OTC label about Zyrtec withdrawal either. Summary: We study how severe was Heart palpitations, when it was recovered, drug effectiveness, race, and more among people who take Zyrtec. This time, I must come off of it, I have to do it quickly, and there is no option but success, so I wanted to thank you for very much for posting your article with tips and tricks so that I can be assured that patience and perseverance will get me to the other side. 6 years and older: 5 to 10 mg orally once a day Been taking for approximately 6 months. Heres what I did, what meds I took, and how I coped with my 2+ weeks of misery: Patience Patience is the most important thing. I am proud of myself. It took 3 months to finally rid myself of the infestation. Im so incredibly miserable right now on day 5. My child has been on Zyrtec since infancy due to asthma and all sorts of allergies. I make a small commission for purchases made through these links but it doesnt affect you or your pricing. Call your doctor for medical advice about side effects. . (I am a healthy 37 y/o male). https://journals.sagepub.com/doi/10.1177/2042098619859996. Using Zyrtec with other drugs that make you drowsy can worsen this effect. Last updated on Oct 29, 2022. Histamine is a substance produced by the body in response to allergic reactions that triggers immune response symptoms such as watery eyes, runny nose, and sneezing. When the heart cannot pump enough blood to meet the body's demands, this is called heart failure. I decided to Google withdrawals of zyrtec. There are no warnings or guidance with regard to this phenomenon. Some people may also find it difficult to think or make good judgements. My tongue felt about the same. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. I went to the doctor and he advised me to continue with Zyrtec! Plan out when youll start and prepare by getting in theright headspace to tackle this challenge. I work in the medical field (ICU nurse) and not a single person I mention this to has any idea that its a thing. Overall, it was a painful 21+ days dealing with the itching that came with discontinuing the medication. Never dreamed it was a withdrawal from zyrtec. Worth looking at it? Withdrawal from an allergy medication should NOT happen, should NOT take this long, and should NOT make a person miserable for WEEKS. As it spread, I thought maybe poison ivy. rhythm problems (palpitations), or . Well done you! On the occasion Ive taken an Allegra, I will itch again after 24 hours of the dose. and following a low-histamine diet. Wanted to stop Zyrtec/Allertec/Xyzal because it would make me feel fatigued and clouded all day. I recently (literally yesterday) discovered about Zyrtec withdrawals. These include antihistamines such as loratadine (Alavert, Claritin), fexofenadine (Allegra), cetirizine (Zyrtec), levocetirizine (Xyzal), and diphenhydramine (Benadryl), as well as steroid nasal . Three years ago decided to cold turkey with no knowledge that withdrawal from Z was thing. Glad to see it ended for you. I grew up with dogs and never had hives/itchness like this! Fingers crossed that as the year progresses the histamine response lessens and Ill be Z free in 2023. Allergies were terrible but Ive moved so am now off it for good. Zyrtec is an antihistamine that reduces the effects of natural chemical histamine in the body. Apparently, though, I was itching in my sleep and would wake with scratch marks. Follow your doctor's instructions. Weight gain was my reason to stop Zyrtec. After 3 days, I quit. I have been weaning myself off for about nine months! I want to take him off of it but I dont know how to manage environmental and seasonal allergies without it. As a result, we suspect that most people are unaware of this potential problem. -Initial dose: 2.5 mg orally once a day Im glad you found remedies to help with the itch. -Maintenance dose: 2.5 mg orally 2 times a day OR 5 mg orally once a day Id itch a lot in the morning, then have a decent afternoon with only slight discomfort, and at night the the itch would intensify. However, this medication also has the potential to cause sedation. We first heard about cetirizine (Zyrtec) withdrawal itching more than a decade ago. Im so glad I found this blog. She prescribed me an oral and topical steroid. Here we are a month later and my body looks mostly healed. Vitamin C is crucial during illness/ infection and most of us dont get enough in our daily diets. Thinking that a hot bath would help, I sat in one for almost an hour. You should also not drink alcohol while taking either of these medications because it can make these side effects worse. I chronicled the first few days in my last post but I wanted to give readers an in-depth look at the rest of my withdrawal experience. I truly believe that weaning off is the best route. Some will have it better, others worse. I wish I could just stop and take a month off of life but I have a very active lifestyle: exercise regularly, have a super active dog that requires daily walks/hikes, and Im on my feet running around at work all day too. Ive done the tapering down process to quit each time, and the crawling bugs always arrive by Day 2. Some say to taper with childrens liquid Zyrtec because you can dial in the dose reduction more accurately, until you are hardly taking any. 48 hours after my last pill I began itching like crazy. Nasal sprays deliver a decongestant right where you need it. Courtney, oh you poor thing! 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